{"id":116222,"date":"2024-11-05T16:25:16","date_gmt":"2024-11-05T11:25:16","guid":{"rendered":"https:\/\/pni.net.pk\/en\/?p=116222"},"modified":"2024-11-05T16:25:16","modified_gmt":"2024-11-05T11:25:16","slug":"higher-zinc-intake-may-increase-endometriosis-risk","status":"publish","type":"post","link":"https:\/\/pni.net.pk\/en\/latest-health-news\/higher-zinc-intake-may-increase-endometriosis-risk\/","title":{"rendered":"Higher zinc intake may increase endometriosis risk"},"content":{"rendered":"<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">ISLAMABAD, NOV 05 (ONLINE): Zinc is an essential mineral that supports immune function, hormone balance, and cell growth.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">In contrast with previous studies, new research suggests that higher zinc consumption may significantly increase the risk of endometriosis compared to consuming lower amounts.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Experts recommend following current zinc guidelines, ensuring adequate intake without excess, and consulting a professional for guidance as needed.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">A recent study suggests a potential link between higher dietary zinc intake and increased risk of endometriosis in American women compared to those with lower zinc consumption.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Zinc is a trace mineral essential for numerous bodily functions, from insulin production to immune system health. It also plays a role in hormone regulation, DNA and protein synthesis, and cell division and growth.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Our bodies cannot store zinc, so we must obtain it through our diet. However, maintaining the right balance is key, as both too much and too little zinc can disrupt human physiology.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Research has begun to explore zinc\u2019s impact on women\u2019s reproductive health, though our understanding is limited, especially regarding conditions like endometriosis.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">This chronic condition involves endometrial cell growth outside the uterus, affecting about 6\u201310% of women of reproductive age. Endometriosis often leads to pain and potential complications like infertility, which impacts up to 50% of those diagnosed.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">The findings of this study are published in BMC Public HealthTrusted Source.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">\u201cThis study provides important insight into the possible physiologic mechanism of zinc\u2019s role in the development of endometriosis,\u201d said Alexandra Filingeri, DCN, RDN, a doctor of clinical nutrition and certified fertility dietitian, who was not involved in the study, to Medical News Today.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Studying dietary zinc intake and endometriosis risk<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">The current study involved a secondary analysis of data collected from the National Health and Nutrition Examination SurveyTrusted Source conducted between 1999 and 2006, focusing on American women ages 20 to 54.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Participants self-reported their endometriosis diagnosis in a reproductive health questionnaire and documented their dietary zinc consumption by providing 24-hour recalls of their food intake.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Researchers assessed one of these 24-hour recalls to estimate each participant\u2019s usual dietary zinc consumption.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">They also considered various factors that could influence the results, including medications and dietary supplement use, age, body mass index, physical activity levels, smoking status, and more.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">A total of 4,315 women were included in the final sample, and 331 (7.7%) of them reported being diagnosed with endometriosis.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">In terms of demographics, approximately 64% of participants were classified as overweight, 39.4% identified as smokers, and 47% reported using dietary supplements.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">The age distribution showed that about 53% were younger than 40, 33% were between 40 and 50, and 14% were older than 50.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">The researchers conducted multiple statistical analyses to examine the relationship between zinc intake and the risk of endometriosis while considering these various influencing factors.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Higher dietary zinc intake may increase endometriosis risk<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Women who took dietary supplements, exercised moderately, and lived with a partner or had a higher income tended to consume more zinc in their diets.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Interestingly, the researchers initially hypothesized that higher dietary zinc would lower the risk of endometriosis.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">However, they found that higher zinc intake might increase the chance of developing endometriosis.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Women who consumed over 14 milligrams (mg) of zinc daily appeared to have a 60% higher risk of endometriosis compared to those who consumed 8 mg a day or less.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">They observed no statistically significant change in endometriosis risk among those consuming 8 to 14 mg of zinc daily.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Additional analysis revealed that lifestyle or demographic factors like smoking, obesity, or race did not seem to influence the link between higher zinc intake and endometriosis risk.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Filingeri highlighted that \u201cthis research challenges some of the previous literature discussing zinc\u2019s role in reproductive health,\u201d which has reported lower zinc levels in women with endometriosis.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">The authors suggest this difference might be due to how zinc is absorbed and metabolized in studies that look at blood versus urine levels or because earlier studies included smaller sample sizes.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">However, Filingeri indicated that one major limitation of this study is its retrospective nature, as it relied on dietary recall rather than monitoring zinc intake over time.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Ultimately, this observational study can\u2019t prove cause and effect, and more research is needed to understand zinc\u2019s role in endometriosis and women\u2019s reproductive health.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">How might zinc contribute to endometriosis?<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Zinc may play a role in endometriosis by managing the body\u2019s immune responses and reducing oxidative stress, which might contribute to developing endometriosis.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">It also helps control enzymes called matrix metalloproteinases (MMPs), which are important for tissue repair and growth.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">StudiesTrusted Source suggest women with endometriosis might have higher levels of certain types of these enzymes, specifically MMP-2 and MMP-9.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Eliza Whitaker, MS, RDN, a women\u2019s health dietitian and founder of Nourished Nutrition and Fitness, who was not involved in the study, said that these enzymes might contribute to the spread of endometriotic tissue outside its typical location.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">She explained that as these MMPs break down the extracellular matrix (surrounding tissue structure), they promote the release of certain inflammatory molecules and help endometrial cells spread into nearby tissues.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">However, she noted, we think this happens when zinc levels are lowTrusted Source.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">\u201cAnother [potential] mechanism involves a protein that binds zinc after it\u2019s absorbed in the diet, metallothionein,\u201d Whitaker said.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">As people age or when they have chronic inflammation, the amount of metallothionein in the body tends to rise. When metallothionein traps zinc, less zinc is available to help certain enzymes work and block MMPs.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Additionally, \u201cwhile low zinc availability poses a concern, high zinc availability may result in immunosuppression,\u201d added Filingeri.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">This is relevant because endometriosis has been linked to immune dysfunctionTrusted Source and chronic inflammation.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Finally, Whitaker pointed out that high zinc may also \u201cinfluence endometriosisTrusted Source by acting as a metalloestrogen, or a metal [ion] that binds and stimulates estrogen receptors.\u201d<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Endometriosis is an estrogen-dependent condition, meaning it relies on estrogen for its growth and progression. Therefore, zinc in high doses might be an endocrine disruptor, upsetting the body\u2019s hormone balance. This may potentially encourage the development and spread of endometriosis.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Essentially, there are many theories, and we have yet to fully grasp the complex relationship between zinc and endometriosis.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Advice for women on how to consume enough zinc<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Zinc needs may vary among women based on factors like dietary habits and health status.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">The study suggests that around 8 mg of zinc daily from food could be a suitable target for most non-pregnant women, potentially lowering the risk of endometriosis compared to higher intakes.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">This aligns with current National Institutes of Health (NIH) Office of Dietary SupplementsTrusted Source guidelines advising women who are not pregnant to aim for a daily zinc intake of 8 mg. The recommended daily intake for a pregnant person increases to 11 mg of zinc.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">To meet your daily goals, obtain zinc from a variety of whole food sourcesTrusted Source, such as:<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">beef (bottom sirloin, roasted, 3 oz: 3.8 mg zinc)<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">pumpkin seeds (roasted, 1 oz: 2.2 mg zinc)<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">turkey breast (cooked, 3 oz: 1.5 mg zinc)<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">lentils (boiled, half cup: 1.3 mg zinc)<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">plain Greek yogurt (6 oz: 1 mg zinc)<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Oysters are an especially rich source of zinc, containing \u201canywhere from 28.1 to 32 mgTrusted Source of zinc per 3 oz serving, which is double the 14 milligrams a day referenced in this study,\u201d Whitaker noted.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">She cautioned that zinc supplements might cause excessive zinc levels if your diet already provides sufficient amounts.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">So, be mindful of your dietary zinc intake and avoid zinc supplements unless recommended by a doctor or registered dietitian.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Whitaker also suggests checking the zinc content in any supplements you take, as you may unknowingly consume it from multiple sources.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Although diet seems to affect the development of endometriosis, it\u2019s not the sole determinant. Genetics, the immune system, gut microbiota, and environmental factors might also play a role.<\/span><\/p>\n<p class=\"selectable-text copyable-text x15bjb6t x1n2onr6\" dir=\"ltr\"><span class=\"selectable-text copyable-text\">Talk with your doctor or gynecologist if you have concerns about your risk for this condition.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>ISLAMABAD, NOV 05 (ONLINE): Zinc is an essential mineral that supports immune function, hormone balance, and cell growth. In contrast with previous studies, new research suggests that higher zinc consumption may significantly increase the risk of endometriosis compared to consuming lower amounts. Experts recommend following [&#8230;]<\/p>\n<p>\n","protected":false},"author":2,"featured_media":116223,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9821],"tags":[],"class_list":["post-116222","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-health-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.1.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Higher zinc intake may increase endometriosis risk - Pakistan News International<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/pni.net.pk\/en\/latest-health-news\/higher-zinc-intake-may-increase-endometriosis-risk\/\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"Higher zinc intake may increase endometriosis risk - Pakistan News International\" \/>\n<meta name=\"twitter:description\" content=\"ISLAMABAD, NOV 05 (ONLINE): Zinc is an essential mineral that supports immune function, hormone balance, and cell growth. In contrast with previous studies, new research suggests that higher zinc consumption may significantly increase the risk of endometriosis compared to consuming lower amounts. 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In contrast with previous studies, new research suggests that higher zinc consumption may significantly increase the risk of endometriosis compared to consuming lower amounts. Experts recommend following [...]","twitter_image":"https:\/\/pni.net.pk\/en\/wp-content\/uploads\/2024\/11\/zn.jpg","twitter_misc":{"Written by":"News Desk","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/pni.net.pk\/en\/latest-health-news\/higher-zinc-intake-may-increase-endometriosis-risk\/#article","isPartOf":{"@id":"https:\/\/pni.net.pk\/en\/latest-health-news\/higher-zinc-intake-may-increase-endometriosis-risk\/"},"author":{"name":"News Desk","@id":"https:\/\/pni.net.pk\/en\/#\/schema\/person\/2b326eefbddc9c3b180116b6f37cce9f"},"headline":"Higher zinc intake may increase endometriosis risk","datePublished":"2024-11-05T11:25:16+00:00","mainEntityOfPage":{"@id":"https:\/\/pni.net.pk\/en\/latest-health-news\/higher-zinc-intake-may-increase-endometriosis-risk\/"},"wordCount":1301,"publisher":{"@id":"https:\/\/pni.net.pk\/en\/#organization"},"image":{"@id":"https:\/\/pni.net.pk\/en\/latest-health-news\/higher-zinc-intake-may-increase-endometriosis-risk\/#primaryimage"},"thumbnailUrl":"https:\/\/pni.net.pk\/en\/wp-content\/uploads\/2024\/11\/zn.jpg","articleSection":["Health"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/pni.net.pk\/en\/latest-health-news\/higher-zinc-intake-may-increase-endometriosis-risk\/","url":"https:\/\/pni.net.pk\/en\/latest-health-news\/higher-zinc-intake-may-increase-endometriosis-risk\/","name":"Higher zinc intake may increase endometriosis risk - 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